Resveratrol Neuroprotection in a Chronic Mouse Model of Multiple Sclerosis
Resveratrol is a naturally-occurring polyphenol that activates SIRT1, an NAD-dependent deacetylase. SRT501, a pharmaceutical formulation of resveratrol with enhanced systemic absorption, prevents neuronal loss without suppressing inflammation in mice with relapsing experimental autoimmune encephalom...
Main Authors: | Zoe eFonseca-Kelly, Mayssa eNassrallah, Jorge eUribe, Reas S Khan, Kimberly eDine, Mahasweta eDutt, Kenneth S Shindler |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-05-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00084/full |
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