In vivo morphological alterations of TAMs during KCa3.1 inhibition—by using in vivo two-photon time-lapse technology

In vivo morphological alterations of TAMs during KCa3.1 inhibition—by using in vivo two-photon time-lapse technology

Tumor associated macrophages (TAMs) are the mostprevalent cells recruited in the tumor microenvironment (TME). Once recruited, TAMs acquire a pro-tumor phenotype characterized by a typical morphology: ameboid in the tumor core and with larger soma and thick branches in the tumor periphery. Targeting...

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Bibliographic Details
Main Authors: Francesca Massenzio, Marco Cambiaghi, Federica Marchiotto, Diana Boriero, Cristina Limatola, Giuseppina D’Alessandro, Mario Buffelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Ca2+ activated K+ channels
TRAM-34
tumor associated macrophages (TAMs)
immune cells in the glioma
two-photon imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.1002487/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2022.1002487/full

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