Unraveling the role of M1 macrophage and CXCL9 in predicting immune checkpoint inhibitor efficacy through multicohort analysis and single‐cell RNA sequencing

Unraveling the role of M1 macrophage and CXCL9 in predicting immune checkpoint inhibitor efficacy through multicohort analysis and single‐cell RNA sequencing

Abstract The exact function of M1 macrophages and CXCL9 in forecasting the effectiveness of immune checkpoint inhibitors (ICIs) is still not thoroughly investigated. We investigated the potential of M1 macrophage and C‐X‐C Motif Chemokine Ligand 9 (CXCL9) as predictive markers for ICI efficacy, empl...

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Bibliographic Details
Main Authors: Yunfang Yu, Haizhu Chen, Wenhao Ouyang, Jin Zeng, Hong Huang, Luhui Mao, Xueyuan Jia, Taihua Guan, Zehua Wang, Ruichong Lin, Zhenjun Huang, Hanqi Yin, Herui Yao, Kang Zhang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:MedComm
Subjects:
Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3G (APOBEC3G)
C‐X‐C Motif Chemokine Ligand 9 (CXCL9)
immune checkpoint inhibitors
M1 macrophage
multi‐level attention graph neural network
tumor immune microenvironment
Online Access:https://doi.org/10.1002/mco2.471

Internet

https://doi.org/10.1002/mco2.471

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