Enhanced pro-apoptosis gene signature following the activation of TAp63α in oocytes upon γ irradiation

Enhanced pro-apoptosis gene signature following the activation of TAp63α in oocytes upon γ irradiation

Abstract Specialized surveillance mechanisms are essential to maintain the genetic integrity of germ cells, which are not only the source of all somatic cells but also of the germ cells of the next generation. DNA damage and chromosomal aberrations are, therefore, not only detrimental for the indivi...

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Bibliographic Details
Main Authors: Niclas Fester, Elisabeth Zielonka, Jakob Goldmann, Ann-Sophie Frombach, Uta Müller-Kuller, Niklas Gutfreund, Kristina Riegel, Jos G. A. Smits, Enrico Schleiff, Krishnaraj Rajalingam, Huiqing Zhou, Stefan Simm, Volker Dötsch
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04659-2

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https://doi.org/10.1038/s41419-022-04659-2

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