No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects.
To investigate whether alterations in mitochondrial metabolism affect longevity in Drosophila melanogaster, we studied lifespan in various single gene mutants, using inbred and outbred genetic backgrounds. As positive controls we included the two most intensively studied mutants of Indy, which encod...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-06-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1892600?pdf=render |