2-Deoxy-D-glucose inhibits lymphocytic choriomeningitis virus propagation by targeting glycoprotein N-glycosylation

2-Deoxy-D-glucose inhibits lymphocytic choriomeningitis virus propagation by targeting glycoprotein N-glycosylation

Abstract Background Increased glucose uptake and utilization via aerobic glycolysis are among the most prominent hallmarks of tumor cell metabolism. Accumulating evidence suggests that similar metabolic changes are also triggered in many virus-infected cells. Viral propagation, like highly prolifera...

Full description

Bibliographic Details
Main Authors: Lucia Baďurová, Katarína Polčicová, Božena Omasta, Ingrid Ovečková, Eva Kocianová, Jana Tomášková
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Virology Journal
Subjects:
Arenavirus
LCMV
Cell metabolism
Glycolysis
2-Deoxy-D-glucose
Glycoprotein
Online Access:https://doi.org/10.1186/s12985-023-02082-3

Internet

https://doi.org/10.1186/s12985-023-02082-3

Similar Items