Differential Effects of Serotonin Transporter Genotype on Anxiety-Like Behavior and Cognitive Judgment Bias in Mice

Differential Effects of Serotonin Transporter Genotype on Anxiety-Like Behavior and Cognitive Judgment Bias in Mice

In humans, the short allele of a common polymorphism in the serotonin transporter (5-HTT) gene is associated with a higher risk to develop depression and anxiety disorders. Furthermore, individuals carrying this allele are characterized by negative judgment biases, as they tend to interpret ambiguou...

Full description

Bibliographic Details
Main Authors: Viktoria Krakenberg, Vanessa Tabea von Kortzfleisch, Sylvia Kaiser, Norbert Sachser, S. Helene Richter
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
anxiety
serotonin transporter
5-HTT
cognitive judgment bias
pessimism
endophenotype
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2019.00263/full

Internet

https://www.frontiersin.org/article/10.3389/fnbeh.2019.00263/full

Similar Items