Clinical Manifestation of Calreticulin Gene Mutations in Essential Thrombocythemia without Janus Kinase 2 and MPL Mutations: A Chinese Cohort Clinical Study

Clinical Manifestation of Calreticulin Gene Mutations in Essential Thrombocythemia without Janus Kinase 2 and MPL Mutations: A Chinese Cohort Clinical Study

Background: Recently, calreticulin (CALR) gene mutations have been identified in patients with essential thrombocythemia (ET). A high-frequency of ET cases without Janus kinase 2 (JAK2) mutations contain CALR mutations and exhibit clinical characteristics different from those with mutant JAK2. Thus,...

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Bibliographic Details
Main Authors: Chao Sun, Xin Zhou, Zhi-Jian Zou, Hong-Feng Guo, Jian-Yong Li, Chun Qiao
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Calreticulin; Essential Thrombocythemia; Gene Mutation; Janus Kinase 2
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=15;spage=1778;epage=1783;aulast=Sun

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=15;spage=1778;epage=1783;aulast=Sun

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