Targeted Inhibition of the miR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Condition
The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that helps overcoming ethical and allergenic challenges posed in application of neural stem cells (NSCs) in targeted cancer gene therapy. However, the tumor-tropic capacity of hiPSC-derived NSCs (hiPS-NSCs) still has mu...
| Glavni autori: | , , , , , |
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| Format: | Članak |
| Jezik: | English |
| Izdano: |
Wiley
2016-01-01
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| Serija: | Stem Cells International |
| Online pristup: | http://dx.doi.org/10.1155/2016/3598542 |