Anti-Toxoplasma gondii screening of MMV pandemic response box and evaluation of RWJ-67657 efficacy in chronically infected mice

Anti-Toxoplasma gondii screening of MMV pandemic response box and evaluation of RWJ-67657 efficacy in chronically infected mice

Toxoplasmosis is a significant public health concern with limited therapeutic options. The medicines for malaria venture (MMV) developed the pandemic response box (PRB) containing 400 drug-like molecules with broad pathogen activity. The aim of this work is to evaluate PRB compounds for their anti-T...

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Bibliographic Details
Main Authors: Bruna Ramos dos Santos, Amanda Bruno da Silva Bellini Ramos, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Fábio Antônio Colombo, Marcos José Marques, Juliana Quero Reimão
Format: Article
Language:English
Published: Cambridge University Press 2023-11-01
Series:Parasitology
Subjects:
antitoxoplasmic compound
bioinformatics
drug discovery
drug repurposing
mice
pandemic response box
RWJ-67657
screening
Toxoplasma gondii
toxoplasmosis
Online Access:https://www.cambridge.org/core/product/identifier/S0031182023000999/type/journal_article

Internet

https://www.cambridge.org/core/product/identifier/S0031182023000999/type/journal_article

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