Structure and Catalytic Properties of Carboxylesterase Isozymes Involved in Metabolic Activation of Prodrugs
Mammalian carboxylesterases (CESs) comprise a multigene family whose geneproducts play important roles in biotransformation of ester- or amide-type prodrugs. Theyare members of an α,β-hydrolase-fold family and are found in various mammals. It has beensuggested that CESs can be classified into...
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| Format: | Article |
| Language: | English |
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MDPI AG
2008-02-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/13/2/412/ |