Antagonism between wild-type and mutant β-catenin controls hepatoblastoma differentiation via fascin-1

Antagonism between wild-type and mutant β-catenin controls hepatoblastoma differentiation via fascin-1

Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours. Those mutations are mostly heterozygous, which allows the co-expression of wi...

Full description

Bibliographic Details
Main Authors: Caroline Gest, Sandra Sena, Lydia Dif, Véronique Neaud, Robin Loesch, Nathalie Dugot-Senant, Lisa Paysan, Léo Piquet, Terezinha Robbe, Nathalie Allain, Doulaye Dembele, Catherine Guettier, Paulette Bioulac-Sage, Anne Rullier, Brigitte Le Bail, Christophe F. Grosset, Frédéric Saltel, Valérie Lagrée, Sabine Colnot, Violaine Moreau
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:JHEP Reports
Subjects:
Hepatoblastoma
Differentiation
Beta-catenin
Fascin-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923000228

Internet

http://www.sciencedirect.com/science/article/pii/S2589555923000228

Similar Items