Integration of pharmacodynamics, metabolomics and network pharmacology to elucidate the effect of Prunella vulgaris seed oil in the treatment of hyperlipidemia

Integration of pharmacodynamics, metabolomics and network pharmacology to elucidate the effect of Prunella vulgaris seed oil in the treatment of hyperlipidemia

To investigate the lipid-lowering activity of PVSO (a natural oil derived from the mature seeds of Prunella vulgaris L.), supercritical CO2 extraction technology was used to extract, and the components were characterized using GC–MS/MS and LC-MS/MS techniques. The lipid-lowering activity of PVSO was...

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Bibliographic Details
Main Authors: Min Zeng, Xinyi Qin, Tao Yi, Zixuan Liu, Chengfeng Li, Shuna Tan, Shuai Zhang, Tongxin Xie, Jingchen Xie, Ping Wu, Zhimin Zhang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Arabian Journal of Chemistry
Subjects:
Hyperlipidemia
Lipid metabolism
Prunella vulgaris seed oil
Oxidative stress
Metabolomics
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223009486

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http://www.sciencedirect.com/science/article/pii/S1878535223009486

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