Epidermal growth factor receptor activation is essential for kidney fibrosis development

Abstract Fibrosis is the progressive accumulation of excess extracellular matrix and can cause organ failure. Fibrosis can affect nearly every organ including kidney and there is no specific treatment currently. Although Epidermal Growth Factor Receptor (EGFR) signaling pathway has been implicated i...

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Bibliographic Details
Main Authors: Shirong Cao, Yu Pan, Andrew S. Terker, Juan Pablo Arroyo Ornelas, Yinqiu Wang, Jiaqi Tang, Aolei Niu, Sarah Abu Kar, Mengdi Jiang, Wentian Luo, Xinyu Dong, Xiaofeng Fan, Suwan Wang, Matthew H. Wilson, Agnes Fogo, Ming-Zhi Zhang, Raymond C. Harris
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43226-x