The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.

The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.

Increased APOBEC3B mRNA levels are associated with a hypermutator phenotype and poor prognosis in ER-positive breast cancer patients. In addition, a 29.5 kb deletion polymorphism of APOBEC3B, resulting in an APOBEC3A-B hybrid transcript, has been associated with an increased breast cancer risk and t...

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Bibliographic Details
Main Authors: Jingjing Liu, Anieta M Sieuwerts, Maxime P Look, Michelle van der Vlugt-Daane, Marion E Meijer-van Gelder, John A Foekens, Antoinette Hollestelle, John W M Martens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4995039?pdf=render

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http://europepmc.org/articles/PMC4995039?pdf=render

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