Chronic exposure to perfluorohexane sulfonate leads to a reproduction deficit by suppressing hypothalamic kisspeptin expression in mice

Abstract Background Perfluorohexane sulfonate (PFHxS) is a six-carbon perfluoroalkyl sulfonic acid found as an environmental contaminant. This study aims to investigate the effects of PFHxS exposure on female reproduction and the underlying mechanism in mice. Methods Eight-week-old ICR mice were div...

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Bibliographic Details
Main Authors: Xiaorui Yin, Tingting Di, Xinyuan Cao, Zhengnan Liu, Jingyan Xie, Suyun Zhang
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-021-00903-z