The fungicide Mancozeb reduces spheroid attachment onto endometrial epithelial cells through downregulation of estrogen receptor β and integrin β3 in Ishikawa cells

The fungicide Mancozeb reduces spheroid attachment onto endometrial epithelial cells through downregulation of estrogen receptor β and integrin β3 in Ishikawa cells

Mancozeb is a metal-containing ethylene bis-dithiocarbamate fungicide widely used in agriculture. Ethylene thiourea (ETU) is the primary metabolite of Mancozeb. Mancozeb has been associated with spontaneous abortions and abnormal menstruation in women. However, the effects of Mancozeb and ETU on emb...

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Bibliographic Details
Main Authors: Ziyi Wang, Kottawattage S.A. Kottawatta, Suranga P. Kodithuwakku, Thevarathanthrige S. Fernando, Yin-Lau Lee, Ernest H.Y. Ng, William S.B. Yeung, Kai-Fai Lee
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Mancozeb
ETU
Spheroid attachment
Microarray
Endometrial receptivity
Steroid hormone receptors
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651320314433

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http://www.sciencedirect.com/science/article/pii/S0147651320314433

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