SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication

Abstract Viral infection in respiratory tract usually leads to cell death, impairing respiratory function to cause severe disease. However, the diversity of clinical manifestations of SARS-CoV-2 infection increases the complexity and difficulty of viral infection prevention, and especially the high-...

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Bibliographic Details
Main Authors: Pan Pan, Weiwei Ge, Zhiwei Lei, Wei luo, Yuqing Liu, Zhanwen Guan, Lumiao Chen, Zhenyang Yu, Miaomiao Shen, Dingwen Hu, Qi Xiang, Wenbiao Wang, Pin Wan, Mingfu Tian, Yang Yu, Zhen Luo, Xulin Chen, Heng Xiao, Qiwei Zhang, Xujing Liang, Xin Chen, Yongkui Li, Jianguo Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01459-8