The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disease that is characterized by the selective degeneration of upper motor neurons and lower spinal motor neurons, resulting in the progressive paralysis of all voluntary muscles. Approximately 10 % of ALS cases are linked to known ge...

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Bibliographic Details
Main Authors: S.T. Ngo, F.J. Steyn
Format: Article
Language:English
Published: SpringerOpen 2015-01-01
Series:Cell Regeneration
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2045976917300081