Characterization of new substrates targeted by Yersinia tyrosine phosphatase YopH.

YopH is an exceptionally active tyrosine phosphatase that is essential for virulence of Yersinia pestis, the bacterium causing plague. YopH breaks down signal transduction mechanisms in immune cells and inhibits the immune response. Only a few substrates for YopH have been characterized so far, for...

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Bibliographic Details
Main Authors: María Luisa de la Puerta, Antonio G Trinidad, María del Carmen Rodríguez, Jori Bogetz, Mariano Sánchez Crespo, Tomas Mustelin, Andrés Alonso, Yolanda Bayón
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19221593/pdf/?tool=EBI