Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases

Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases

Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-<!-- $MVD$:face("Times") -->DArg-Arg-Leu-EDDnp (Abz-<!-- $MVD$:face("Times") -...

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Bibliographic Details
Main Authors: M.A.S. Medeiros, M.S.F. França, G. Boileau, L. Juliano, K.M. Carvalho
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1997-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
neutral endopeptidase
enkephalinase
neprilysin
fluorogenic substrates
phosphoramidon
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000003

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000003

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