Nationwide epidemiological survey of Leber hereditary optic neuropathy in Japan

Nationwide epidemiological survey of Leber hereditary optic neuropathy in Japan

Background: Leber hereditary optic neuropathy (LHON) is a maternally inherited optic neuropathy that leads to central loss of vision, predominantly in young males. Most LHON cases have one of three primary point mutations in mitochondrial DNA (mtDNA). The annual incidence and prevalence of LHON in J...

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Bibliographic Details
Main Author: Kaori Ueda
Format: Article
Language:English
Published: Japan Epidemiological Association 2017-09-01
Series:Journal of Epidemiology
Subjects:
Annual incidence
Gender proportion
Leber hereditary optic neuropathy
Mitochondrial DNA
Penetrance
Online Access:https://www.jstage.jst.go.jp/article/jea/27/9/27_JE73/_pdf

Internet

https://www.jstage.jst.go.jp/article/jea/27/9/27_JE73/_pdf

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