Immune checkpoint blockade: timing is everything

Neoadjuvant immunotherapy effectively uses the in situ tumor as a reservoir of tumor antigens to promote systemic antitumor immunity. Studies indicate that intratumoral responses to immune checkpoint inhibitors (ICIs) are mediated by resident memory T cells cells that are sequestered in tumors and h...

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Bibliographic Details
Main Authors: Frank A Sinicrope, Mary Jo Turk
Format: Article
Language:English
Published: BMJ Publishing Group 2024-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/8/e009722.full