Extracellular vesicles from organoid‐derived human retinal progenitor cells prevent lipid overload‐induced retinal pigment epithelium injury by regulating fatty acid metabolism

Extracellular vesicles from organoid‐derived human retinal progenitor cells prevent lipid overload‐induced retinal pigment epithelium injury by regulating fatty acid metabolism

Abstract Retinal degeneration (RD), a group of diseases leading to irreversible vision loss, is characterised by retinal pigment epithelium (RPE) or retinal neuron damage and loss. With fewer risks of immune rejection and tumorigenesis, stem cell‐secreted extracellular vesicles (EVs) offer a new cel...

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Bibliographic Details
Main Authors: Hui Gao, Yuxiao Zeng, Xiaona Huang, Luodan A, Qingle Liang, Jing Xie, Xi Lin, Jing Gong, Xiaotang Fan, Ting Zou, Haiwei Xu
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
lipid metabolism
retinal organoids
retinal pigment epithelium cells
retinal progenitor cells
Online Access:https://doi.org/10.1002/jev2.12401

Internet

https://doi.org/10.1002/jev2.12401

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