Simvastatin induced ferroptosis for triple-negative breast cancer therapy

Simvastatin induced ferroptosis for triple-negative breast cancer therapy

Abstract Triple-negative breast cancer (TNBC), a management of aggressive breast cancer, remains an unmet medical challenge. Although a wave of efforts had spurred to design novel therapeutic method of TNBC, unpredictable prognosis with lacking effective therapeutic targets along with the resistance...

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Bibliographic Details
Main Authors: Xianxian Yao, Ruihong Xie, Yongbin Cao, Jing Tang, Yongzhi Men, Haibao Peng, Wuli Yang
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Nanobiotechnology
Subjects:
Triple-negative breast cancer
Ferroptosis
Simvastatin
Long circulation
Controlled release
Online Access:https://doi.org/10.1186/s12951-021-01058-1

Internet

https://doi.org/10.1186/s12951-021-01058-1

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