Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice

Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice

Reverse vaccinology or immunoinformatics is a computational methodology which integrates data from in silico epitope prediction, associated to other important information as, for example, the predicted subcellular location of the proteins used in the design of the context of vaccine development. Thi...

Full description

Bibliographic Details
Main Authors: Rory Cristiane Fortes De Brito, Jamille Mirelle de Oliveira Cardoso, Levi Eduardo Soares Reis, Fernando Augusto Siqueira Mathias, Rodrigo Dian de Oliveira Aguiar-Soares, Andréa Teixeira-Carvalho, Bruno Mendes Roatt, Rodrigo Corrêa-Oliveira, Jeronimo Conceição Ruiz, Daniela de Melo Resende, Alexandre Barbosa Reis
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Vaccines
Subjects:
reverse vaccinology
immunoinformatics
peptide-based vaccine
<i>leishmania infantum</i>
polyfunctional t-cells
memory t-cells
rational design of vaccines
Online Access:https://www.mdpi.com/2076-393X/7/4/162

Internet

https://www.mdpi.com/2076-393X/7/4/162

Similar Items