A primary rat neuron-astrocyte-microglia tri-culture model for studying mechanisms of neurotoxicity
Primary cell cultures from rodent brain are widely used to investigate molecular and cellular mechanisms of neurotoxicity. To date, however, it has been challenging to reliably culture endogenous microglia in dissociated mixed cultures. This is a significant limitation of most in vitro neural cell m...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-01-01
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Series: | Frontiers in Toxicology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/ftox.2024.1523387/full |