Radiation upregulates macrophage TREM-1 expression to exacerbate injury in mice

Radiation upregulates macrophage TREM-1 expression to exacerbate injury in mice

IntroductionExposure to high-dose ionizing radiation causes tissue injury, infections and even death due to immune dysfunction. The triggering receptor expressed on myeloid cells-1 (TREM-1) has been demonstrated to critically amplify and dysregulate immune responses. However, the role of TREM-1 in r...

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Bibliographic Details
Main Authors: Satoshi Yamaga, Atsushi Murao, Gaifeng Ma, Max Brenner, Monowar Aziz, Ping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
TREM-1
macrophage
ionizing radiation
eCIRP
DAMP
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151250/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151250/full

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