Humanin, a cytoprotective peptide, is expressed in carotid atherosclerotic [corrected] plaques in humans.

The mechanism of atherosclerotic plaque progression leading to instability, rupture, and ischemic manifestation involves oxidative stress and apoptosis. Humanin (HN) is a newly emerging endogenously expressed cytoprotective peptide. Our goal was to determine the presence and localization of HN in ca...

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Bibliographic Details
Main Authors: David G Zacharias, Sung Gyun Kim, Alfonso Eirin Massat, Adi R Bachar, Yun K Oh, Joerg Herrmann, Martin Rodriguez-Porcel, Pinchas Cohen, Lilach O Lerman, Amir Lerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3273477?pdf=render