Investigation of frequent somatic mutations of MTND5 gene in gastric cancer cell lines and tissues

Investigation of frequent somatic mutations of MTND5 gene in gastric cancer cell lines and tissues

The present study investigated the single nucleotide variants (SNVs) in mitochondrial DNA (mtDNA) of 13 paired gastric cancer tissue samples and seven gastric cancer cell lines using direct sequencing analysis of the MTND5 region. Results showed that nuclear mitochondrial pseudogenes (NUMTs) and mit...

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Bibliographic Details
Main Authors: Lian Li, Rui Xing, Jiantao Cui, Wenmei Li, Youyong Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Mitochondrial DNA. Part B. Resources
Subjects:
gastric cancer
mitochondrial nd5 gene
nuclear mitochondrial pseudogenes
single nucleotide variation
single nucleotide polymorphism
Online Access:http://dx.doi.org/10.1080/23802359.2018.1501287

Internet

http://dx.doi.org/10.1080/23802359.2018.1501287

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