High-resolution cryo-EM reconstructions in the presence of substantial aberrations

High-resolution cryo-EM reconstructions in the presence of substantial aberrations

Here, an analysis is performed of how uncorrected antisymmetric aberrations, such as coma and trefoil, affect cryo-EM single-particle reconstruction (SPR) results, and an analytical formula quantifying information loss owing to their presence is inferred that explains why Fourier-shell coefficient-b...

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Bibliographic Details
Main Authors: Raquel Bromberg, Yirui Guo, Dominika Borek, Zbyszek Otwinowski
Format: Article
Language:English
Published: International Union of Crystallography 2020-05-01
Series:IUCrJ
Subjects:
cryo-em
axial aberrations
coma
trefoil
resolution
validation
3d reconstruction and image processing
automation
single-particle cryo-em
imaging
structure determination
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252520002444

Internet

http://scripts.iucr.org/cgi-bin/paper?S2052252520002444

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