Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus.

Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus.

The fungus Aspergillus fumigatus is a leading infectious killer in immunocompromised patients. Calcineurin, a calmodulin (CaM)-dependent protein phosphatase comprised of calcineurin A (CnaA) and calcineurin B (CnaB) subunits, localizes at the hyphal tips and septa to direct A. fumigatus invasion and...

Full description

Bibliographic Details
Main Authors: Praveen R Juvvadi, Christopher Gehrke, Jarrod R Fortwendel, Frédéric Lamoth, Erik J Soderblom, Erik C Cook, Michael A Hast, Yohannes G Asfaw, M Arthur Moseley, Trevor P Creamer, William J Steinbach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3749960?pdf=render

Internet

http://europepmc.org/articles/PMC3749960?pdf=render

Similar Items