Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

<p>Abstract</p> <p>Background</p> <p>Cis-Platinum (II) (cis-diammine dichloroplatinum; CDDP) is a potent antitumor compound widely used for the treatment of many malignancies. An important side-effect of CDDP is nephrotoxicity. The cytotoxic action of this drug is often...

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Bibliographic Details
Main Authors: Brahmi Dalel, Ayed Yousra, Hfaiedh Mbarka, Bouaziz Chayma, Mansour Hedi Ben, Zourgui Lazhar, Bacha Hassen
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Cactus
CDDP
Genotoxicity
Antioxidant
Protective effect
Online Access:http://www.biomedcentral.com/1472-6882/12/111

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http://www.biomedcentral.com/1472-6882/12/111

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