Effects of lung cancer cell-associated B7-H1 on T-cell proliferation in vitro and in vivo

Effects of lung cancer cell-associated B7-H1 on T-cell proliferation in vitro and in vivo

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B7 homolog 1 (B7-H1) is the most potent immunoinhibitory molecule in the B7 family. In this study, we examined the effects of tumor-associated B7-H1 on T-cell proliferation in lung cancer. The expression of B7-H1 in human adenocarcinoma A549 and mouse Lewis lung carcinoma (LLC) cells were examined b...

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Bibliographic Details
Main Authors: K. Chen, H.T. Huang, W.J. Hang, L.B. Pan, H.T. Ma
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2016-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Costimulatory molecule
B7-H1
A549
Lewis lung carcinoma
Immunosuppression
T-cell proliferation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000700701&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000700701&lng=en&tlng=en

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