Reticulon 2 promotes gastric cancer metastasis via activating endoplasmic reticulum Ca2+ efflux-mediated ERK signalling

Abstract Gastric cancer ranks fourth for mortality globally among various malignant tumours, and invasion and metastasis are the major reason leading to its poor prognosis. Recently, accumulating studies revealed the role of reticulon proteins in cell growth and transmigration. However, the expressi...

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Bibliographic Details
Main Authors: Shushu Song, Bo Liu, Xiaoqing Zeng, Yingying Wu, Hao Chen, Hao Wu, Jianxin Gu, Xiaodong Gao, Yuanyuan Ruan, Hongshan Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04757-1