Validation of an Automated Quantitative Digital Pathology Approach for Scoring TMEM: A Prognostic Biomarker for Metastasis

Validation of an Automated Quantitative Digital Pathology Approach for Scoring TMEM: A Prognostic Biomarker for Metastasis

Metastasis causes ~90% of breast cancer mortality. However, standard prognostic tests based mostly on proliferation genes do not measure metastatic potential. Tumor MicroEnvironment of Metastasis (TMEM), an immunohistochemical biomarker for doorways on blood vessels that support tumor cell dissemina...

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Bibliographic Details
Main Authors: David Entenberg, Maja H. Oktay, Timothy D’Alfonso, Paula S. Ginter, Brian D. Robinson, Xiaonan Xue, Thomas E. Rohan, Joseph A. Sparano, Joan G. Jones, John S. Condeelis
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
TMEM
metastasis
prognostic
digital pathology
validation study
Online Access:https://www.mdpi.com/2072-6694/12/4/846

Internet

https://www.mdpi.com/2072-6694/12/4/846

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