Polyphenolic-enriched olive leaf extract attenuated doxorubicin-induced cardiotoxicity in rats via suppression of oxidative stress and inflammation

Abstract Background The therapeutic value of doxorubicin as an effective anti-neoplastic agent is limited by its cardiotoxic side effects. We investigated the effects of ethanolic leaf extracts of olive leaf OL on cardiotoxicity as well as oxidative stress which was induced by doxorubicin (DOX) in W...

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Bibliographic Details
Main Authors: Alaaeldin Ahmed Hamza, Soha Osama Hassanin, Salsabil Hamza, Ali Abdalla, Amr Amin
Format: Article
Language:English
Published: SpringerOpen 2021-10-01
Series:Journal of Basic and Applied Zoology
Subjects:
Online Access:https://doi.org/10.1186/s41936-021-00251-w