Microglia depletion prevents lactation by inhibition of prolactin secretion

Summary: Microglial cells were eliminated from the brain with sustained 3–4 weeks long inhibition of colony stimulating factor 1 receptor by Pexidartinib 3397 (PLX3397). The prepartum treated mice mothers did not feed their pups after parturition. The pups of mothers treated orally only in the postp...

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Bibliographic Details
Main Authors: Vivien Csikós, Szilvia Oláh, Fanni Dóra, Nikolett Arrasz, Melinda Cservenák, Arpád Dobolyi
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223003413