Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.

Recent outbreaks of the Ebola virus (EBOV) have focused attention on the dire need for antivirals to treat these patients. We identified pyronaridine tetraphosphate as a potential candidate as it is an approved drug in the European Union which is currently used in combination with artesunate as a tr...

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Bibliographic Details
Main Authors: Thomas R Lane, Christopher Massey, Jason E Comer, Manu Anantpadma, Joel S Freundlich, Robert A Davey, Peter B Madrid, Sean Ekins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007890