Beneath the surface: Amino acid variation underlying two decades of dengue virus antigenic dynamics in Bangkok, Thailand.

Neutralizing antibodies are important correlates of protection against dengue. Yet, determinants of variation in neutralization across strains within the four dengue virus serotypes (DENV1-4) is imperfectly understood. Studies focus on structural DENV proteins, especially the envelope (E), the prima...

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Bibliographic Details
Main Authors: Angkana T Huang, Henrik Salje, Ana Coello Escoto, Nayeem Chowdhury, Christian Chávez, Bernardo Garcia-Carreras, Wiriya Rutvisuttinunt, Irina Maljkovic Berry, Gregory D Gromowski, Lin Wang, Chonticha Klungthong, Butsaya Thaisomboonsuk, Ananda Nisalak, Luke M Trimmer-Smith, Isabel Rodriguez-Barraquer, Damon W Ellison, Anthony R Jones, Stefan Fernandez, Stephen J Thomas, Derek J Smith, Richard Jarman, Stephen S Whitehead, Derek A T Cummings, Leah C Katzelnick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010500