Hepatotoxicity during TB treatment in people with HIV/AIDS related to NAT2 polymorphisms in Pernambuco, Northeast Brazil

Hepatotoxicity during TB treatment in people with HIV/AIDS related to NAT2 polymorphisms in Pernambuco, Northeast Brazil

Introduction and objective: Hepatotoxicity during tuberculosis (TB) treatment is frequent and may be related to the Arylamine N-Acetyltransferase (NAT2) acetylator profile, in which allele frequencies differ according to the population. The aim of this study was to investigate functional polymorphis...

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Bibliographic Details
Main Authors: Carolline Araujo-Mariz, Maria de Fátima P. Militão de Albuquerque, Edmundo P. Lopes, Ricardo A.A. Ximenes, Heloísa R. Lacerda, Demócrito B. Miranda-Filho, Brena B. Lustosa-Martins, André Filipe P. Pastor, Bartolomeu Acioli-Santos
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Annals of Hepatology
Subjects:
Arylamine N-acetyltransferase
Liver disease
Toxicity
Antitubercular drugs
Co-infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119322598

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http://www.sciencedirect.com/science/article/pii/S1665268119322598

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