LFA1 Activation: Insights from a Single-Molecule Approach

Integrin LFA1 is a cell adhesion receptor expressed exclusively in leukocytes, and plays crucial roles in lymphocyte trafficking, antigen recognition, and effector functions. Since the discovery that the adhesiveness of LFA1 can be dynamically changed upon stimulation, one challenge has been underst...

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Bibliographic Details
Main Authors: Naoyuki Kondo, Yoshihiro Ueda, Tatsuo Kinashi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/11/1751