Is it Possible to Obtain Immunofluorescence Data in Formalin-Fixed Paraffin-Embedded Skin Samples for the Diagnosis of Pemphigus Vulgaris and Bullous Pemphigoid

Is it Possible to Obtain Immunofluorescence Data in Formalin-Fixed Paraffin-Embedded Skin Samples for the Diagnosis of Pemphigus Vulgaris and Bullous Pemphigoid

Objective: The gold-standard method for assessment of autoimmune bullous disease is direct/indirect immunofluorescence (IF) examination applied to fresh frozen tissue. Since the sensitivity of IF is greatly reduced in formalin-fixed paraffin-embedded (FFPE) tissues, IF cannot be relied upon in these...

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Bibliographic Details
Main Authors: Deniz ATES OZDEMIR, Ozay GOKOZ, Arzu SAGLAM
Format: Article
Language:English
Published: Federation of Turkish Pathology Societies 2024-01-01
Series:Türk Patoloji Dergisi
Subjects:
protease digestion
igg
pemphigus vulgaris
bullous pemphigoid
c4d
Online Access:https://turkjpath.org/pdf.php?id=2047

Internet

https://turkjpath.org/pdf.php?id=2047

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