Construction of a recombinant avipoxvirus expressing the env gene of Zika virus as a novel putative preventive vaccine

Abstract Background Zika virus (ZIKV) has been declared a public health emergency that requires development of an effective vaccine, as it might represent an international threat. Methods Here, two novel DNA-based (pVAXzenv) and fowlpox-based (FPzenv) recombinant putative vaccine candidates were con...

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Bibliographic Details
Main Authors: Carlo Zanotto, Francesca Paolini, Antonia Radaelli, Carlo De Giuli Morghen
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-021-01519-x