COSMC is overexpressed in proliferating infantile hemangioma and enhances endothelial cell growth via VEGFR2.

COSMC is overexpressed in proliferating infantile hemangioma and enhances endothelial cell growth via VEGFR2.

Infantile hemangiomas are localized lesions comprised primarily of aberrant endothelial cells. COSMC plays a crucial role in blood vessel formation and is characterized as a molecular chaperone of T-synthase which catalyzes the synthesis of T antigen (Galβ1,3GalNAc). T antigen expression is associat...

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Bibliographic Details
Main Authors: Jian Lee, Chia-Hua Chen, Ya-Hsin Chen, Miao-Juei Huang, John Huang, Ji-Shiang Hung, Ming-Ting Chen, Min-Chuan Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3570459?pdf=render

Internet

http://europepmc.org/articles/PMC3570459?pdf=render

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