Differentiation of mouse embryonic stem cells into cells with spermatogonia-like morphology with chemical intervention-dependent increased gene expression of LIM homeobox 1 (Lhx1)

Differentiation of mouse embryonic stem cells into cells with spermatogonia-like morphology with chemical intervention-dependent increased gene expression of LIM homeobox 1 (Lhx1)

Spermatogonial stem cells (SSCs) originate from gonocytes that differentiate from primordial germ cells (PGCs). In the developing mouse testis, expression of the gene LIM homeobox 1 (Lhx1) marks the most undifferentiated SSCs, which has not yet been reported for spermatogonia-like cells generated in...

Full description

Bibliographic Details
Main Authors: Cameron Moshfegh, Sebastian G. Rambow, Seraina A. Domenig, Aldona Pieńkowska-Schelling, Ulrich Bleul, Viola Vogel
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Stem Cell Research
Subjects:
Lhx1
Spermatogonia development
Male germline
Embryonic stem cells
In vitro culture system
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122001295

Internet

http://www.sciencedirect.com/science/article/pii/S1873506122001295

Similar Items