Rapid and sensitive point-of-care detection of Leptospira by RPA-CRISPR/Cas12a targeting lipL32.

Rapid and sensitive point-of-care detection of Leptospira by RPA-CRISPR/Cas12a targeting lipL32.

<h4>Background</h4>One of the key barriers preventing rapid diagnosis of leptospirosis is the lack of available sensitive point-of-care testing. This study aimed to develop and validate a clustered regularly-interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 12a (CRI...

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Bibliographic Details
Main Authors: Sirawit Jirawannaporn, Umaporn Limothai, Sasipha Tachaboon, Janejira Dinhuzen, Patcharakorn Kiatamornrak, Watchadaporn Chaisuriyong, Jom Bhumitrakul, Oraphan Mayuramart, Sunchai Payungporn, Nattachai Srisawat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010112&type=printable

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https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010112&type=printable

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