Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity

Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity

Background and objectives: eNAMPT (extracellular nicotinamide phosphoribosyltransferase), a novel DAMP and TLR4 ligand, is a druggable ARDS therapeutic target with NAMPT promoter SNPs associated with ARDS severity. This study assesses the previously unknown influence of NAMPT promoter SNPs on NAMPT...

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Bibliographic Details
Main Authors: Heather Lynn, Xiaoguang Sun, Nancy G. Casanova, Christian Bime, Vivian Reyes Hernon, Clayton Lanham, Radu C. Oita, Nikolas Ramos, Belinda Sun, Dawn K. Coletta, Sara M. Camp, Jason H. Karnes, Nathan A. Ellis, Joe G.N. Garcia
Format: Article
Language:English
Published: SAGE Publishing 2023-07-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/17534666231181262

Internet

https://doi.org/10.1177/17534666231181262

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