3D In Vitro Model of a Functional Epidermal Permeability Barrier from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

3D In Vitro Model of a Functional Epidermal Permeability Barrier from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

Cornification and epidermal barrier defects are associated with a number of clinically diverse skin disorders. However, a suitable in vitro model for studying normal barrier function and barrier defects is still lacking. Here, we demonstrate the generation of human epidermal equivalents (HEEs) from...

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Bibliographic Details
Main Authors: Anastasia Petrova, Anna Celli, Laureen Jacquet, Dimitra Dafou, Debra Crumrine, Melanie Hupe, Matthew Arno, Carl Hobbs, Aleksandra Cvoro, Panagiotis Karagiannis, Liani Devito, Richard Sun, Lillian C. Adame, Robert Vaughan, John A. McGrath, Theodora M. Mauro, Dusko Ilic
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114000885

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http://www.sciencedirect.com/science/article/pii/S2213671114000885

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