Matrix density regulates adipocyte phenotype

Matrix density regulates adipocyte phenotype

ABSTRACTAlterations of the extracellular matrix contribute to adipose tissue dysfunction in metabolic disease. We studied the role of matrix density in regulating human adipocyte phenotype in a tunable hydrogel culture system. Lipid accumulation was maximal in intermediate hydrogel density of 5 weig...

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Bibliographic Details
Main Authors: Alexander Ky, Atticus J. McCoy, Carmen G. Flesher, Nicole E. Friend, Jie Li, Kore Akinleye, Christopher Patsalis, Carey N. Lumeng, Andrew J. Putnam, Robert W. O’Rourke
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Adipocyte
Subjects:
Adipocyte
adipogenesis
adipose tissue
matrix
hydrogel
Online Access:https://www.tandfonline.com/doi/10.1080/21623945.2023.2268261

Internet

https://www.tandfonline.com/doi/10.1080/21623945.2023.2268261

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